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November 07.2025

2 Minutes Read

Understanding Medications That Impact CGM Accuracy for Better Diabetes Management

Medications that impact CGM accuracy: CGM and acetaminophen.

The Impact of Medications on CGM Accuracy

Continuous Glucose Monitors (CGMs) have transformed diabetes management for many individuals, providing insights into glucose levels that were previously difficult to obtain. However, the effectiveness of these devices can be compromised by certain medications and supplements. Understanding these interactions is vital for diabetes care, as inaccurate readings may lead to dangerous decisions concerning insulin and dietary choices.

Why Medications Affect CGM Readings

CGMs measure glucose levels through electrochemical sensors in the interstitial fluid, which can be influenced by various medications. These drugs may either contain electroactive elements or induce metabolic changes that interfere with the sensor's readings. For instance, substances like acetaminophen can produce chemical reactions leading to erroneous glucose values.

Common Medications That Can Interfere with CGMs

1. Acetaminophen (Tylenol): High doses can falsely elevate glucose readings on some CGM systems by affecting sensor reactions. It's especially problematic for the Dexcom systems and may lead to a misunderstanding of actual blood sugar levels. Always cross-check with a fingerstick if readings seem unusual.

2. High-Dose Vitamin C: Known to produce falsely high readings, different CGM brands have varying sensitivity to vitamin C. FreeStyle Libre users should be cautious if taking doses higher than 500mg per day, as this can lead to missed low glucose warnings.

3. Aspirin: While not as problematic in newer models, salicylates associated with aspirin can potentially lower glucose readings by altering the interstitial fluid's chemistry, affecting the sensor’s accuracy.

4. Hydroxyurea: This medication directly interferes with CGM readings, resulting in falsely elevated blood sugar readings. Users of Dexcom CGMs are specifically warned against its use while monitoring glucose levels.

Keeping Your CGM Accurate

To ensure CGM accuracy, it's crucial to communicate with healthcare providers about any medications you're taking. Regularly cross-check sensor readings with fingerstick tests when trying out new medications or experiencing unexpected results. Being informed allows for better management of diabetes and can significantly improve quality of life.

In conclusion, understanding the intersection of medications and CGMs is essential for effective diabetes management. By staying aware of how certain substances can impact glucose readings, users can make informed health decisions and seek guidance from healthcare professionals as needed.

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Understanding Medications That Impact CGM Accuracy for Better Diabetes Management

The Impact of Medications on CGM Accuracy

Why Medications Affect CGM Readings

Common Medications That Can Interfere with CGMs

Keeping Your CGM Accurate

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